Watermelon extract reduces blood pressure but does not...
Watermelon extract reduces blood pressure but does not change the sympathovagal balance in prehypertensive and hypertensive subjects
Author(s): Massa NM et al.
J / D / DOI: Blood pressure / 08-2016 / 10.3109/08037051.2016.1150561
More study details
- Study population (Humans)
- Number of test entities:
- total (40) / substance group (20) / control group (20)
- Study type (randomized controlled trial)
- Study duration:
- days (42)
Major areas of study (META): Watermelon extract intake lowers blood pressure in prehypertensive and hypertensive individuals, but does not alter the cardiac autonomic modulation.
Abstract
Previous studies have shown that watermelon extract reduces blood pressure through vasodilation. However, those studies have not verified whether sympathetic nervous activity is influenced by watermelon extract. This study aimed to evaluate the effect of supplementation with watermelon extract for 6 weeks on blood pressure and sympathovagal balance of prehypertensive and hypertensive individuals.
Forty volunteers participated in a randomized, double-blind, experimental and placebo-controlled study. They consumed 6 g of watermelon extract daily (n = 20; age 48.7 ± 1.9 years, 10 men) or a placebo (n = 20; age 47.4 ± 1.2 years, 11 men) for 6 weeks. Blood pressure and cardiac autonomic modulation were measured.
Watermelon extract promoted a significant reduction in systolic (137.8 ± 3.9 to 126.0 ± 4.0 mmHg, p < 0.0001) and diastolic (79.2 ± 2.2 to 72.3 ± 2.0 mmHg, p < 0.001) blood pressure, but showed no differences compared to the placebo group. This significant reduction in blood pressure occurred without a significant change in sympathovagal balance from the beginning (1.7 ± 0.1) to the end of the study (1.7 ± 0.4).
In conclusion, supplementation with watermelon extract reduces systolic and diastolic blood pressure in prehypertensive and hypertensive individuals, but does not alter the cardiac autonomic modulation of these individuals.
Cite as (Vancouver style)
Massa NM, Silva AS, Toscano LT, Silva JD, Persuhn DC, Gonçalves Mda C. Watermelon extract reduces blood pressure but does not change sympathovagal balance in prehypertensive and hypertensive subjects. Blood Press. 2016 Aug;25(4):244-8.
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